Using CPU affinity, you can assign a virtual machine to a specific processor. This allows you to restrict the assignment of virtual machines to a specific available processor in multiprocessor systems.
Procedure
Browse to the virtual machine in the vSphere Client.
To find a virtual machine, select a data center, folder, cluster, resource pool, or host.
Select VMs.
Right-click the virtual machine and click Edit Settings.
Under Virtual Hardware, expand CPU.
Under Scheduling Affinity, select physical processor affinity for the virtual machine.
Use ‘-‘ for ranges and ‘,’ to separate values.
For example, “0, 2, 4-7” would indicate processors 0, 2, 4, 5, 6 and 7.
Select the processors where you want the virtual machine to run and click OK.